Topology-Dependent T2 Relaxivity in Fe3O Cluster-Based MOFs for Enhanced Tumor Monitoring via MRI, Qiao Wang, Yimin Gong, Jianing Li, Xin Zeng, Dan Luo, Yun Ling*, Yaming Zhou and Zhenxia Chen*;Journal of Materials Chemistry B, , 2025, ASAP >> Fulltext link
Coordination-Dissociation Induced T1-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring, Dan Luo, Tianze Wu, Tianze Qiu, Jianing Li, Yimin Gong, Jingting Weng, Zhenxia Chen, Yannan Yang, Bo Yin, Yun Ling*, Yaming Zhou Adv. Funct. Mater. , 2025, ASAP >> Fulltext link
Photocaging of N-pyridinyl amide scaffold-based PIM inhibitors for spatiotemporal controlled anticancer bioactivity, Mingzhu Lu, Haifeng Liu, Ruiqing Xiang, Jianing Li, Tianze Wu, Mingli Deng, Yu Jia, Xiaofeng Liu, Yongtai Yang, Yu Ge, Tong Cai , Jianming Wu*, Yun Ling, Yaming Zhou*Bioorganic & Medicinal Chemistry, 2025，118159 >> Fulltext link
Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications , Yimin Gong, Hui Zhang, Mingzhu Lu, Jiayu Sun, Yu Jia, Yannan Yang, Xiaofeng Liu, Bo Yin, Yaming Zhou, Yun Ling, Journal of Colloid and Interface Science, 2025, 479, 412-421 >> Fulltext link
Hybrid nanoparticle–mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines, Jianing Li, Tianze Wu, Weidong Wang, Yimin Gong, Mingzhu Lu, Mengmeng Zhang, Wanyue Lu, Yaming Zhou*, Yannan Yang* Sci. Adv. , 2024, 10, eadn3002 >> Fulltext link
A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis , Wanyue Lu, Weidong Wang, Yimin Gong, Jianing Li, Yaming Zhou*, Yannan Yang*, Small, 2024, 202407676 >> Fulltext link
Tadpole-like carbon nanotube with Fe nanoparticle encapsulated at the head and Zn single-atom anchored on the body: one-pot carbonization for tetramodal synergistic cancer therapy , Mengmeng Zhang, Mingzhu Lu, Yimin Gong, Yannan Yang*, Junfei Song, Jianing Li, Zhenxia Chen, Yun Ling*, Yaming Zhou, Small, 2024, 2400587 >> Fulltext link
Discovery of two predictable (3,18)-connected topologies based on Wells–Dawson type cages for the design of porous metal phosphonocarboxylate frameworks , Wenyan Dan, Zhenxia Chen,* Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu and Mingli Deng Dalton Transcations, 2024,53, 7734-7741>> Fulltext link
Mesoporous carbon hemispheres integrated with Fe–Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy , Mengmeng Zhang, Tianze Wu, Hui Zhang, Zhenxia Chen, Yannan Yang, Yun Ling * and Yaming Zhou,* Journal of Materials Chemistry B, 2024, 12, 658-666 >> Fulltext link
Systematical Evaluation of the Structure-Cardiotoxicity Relationship of 7-Azaindazole-based PI3K Inhibitors Designed by Bioisosteric Approach , Tianze Wu, Yi Chen, Chengbin Yang, Mingzhu Lu, Fang Geng, Jianhua Guo, Yan Pi, Yun Ling, Jun Xu, Tong Cai, Lei Lu & Yaming Zhou,* Cardiovascular Toxicology, 2023, 23, 364-376 >> Fulltext link
Discovery and identification of a novel PI3K inhibitor with enhanced CDK2 inhibition for the treatment of triple negative breast cancer , Chengbin Yang, Menghui Wang, Yimin Gong, Mingli Deng, Yun Ling, Qingquan Li, Jianxin Wang*, Yaming Zhou,* Bioorganic Chemistry, 2023, 140, 106779 >> Fulltext link
Discovery of a photosensitizing PI3K inhibitor for tumor therapy: Design, synthesis and in vitro biological evaluation , Chengbin Yang, Yimin Gong, Mingli Deng, Yun Ling, Jianxin Wang*, Yaming Zhou,* Bioorganic & Medicinal Chemistry Letters, 2023,94, 129459 >> Fulltext link
Reticular chemistry of the fcu-type Gd(III)-doped metal-organic framework for T1-weighted magnetic resonance imaging，Tianze Qiu; Tianze Wu; Mingzhu Lu; Yuxi Xie; Mengmeng Zhang; Dan Luo; Zhenxia Chen; Bo Yin; Yaming Zhou; Yun Ling,* Small, 2023, 2303063 >> Fulltext link
Discovery of N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide (FD274) as a highly potent PI3K/mTOR dual inhibitor for the treatment of acute myeloid leukemia , Chengbin Yang, Yi Chen, Tianze Wu, Yunjian Gao, Xiaofeng Liu, Yongtai Yang, Yun Ling, Yu Jia, Mingli Deng*, Jianxin Wang, Yaming Zhou,* European Journal of Medicinal Chemistry, 2023, 258, 115543 >> Fulltext link
Nanosheets of two-dimensional photoluminescent Lanthanide phosphonocarboxylate frameworks decorated with free carboxylic groups for latent fingerprint imaging , Dan Luo, Hongjie He, Huiru Jing, Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu, Zhenxia Chen* and Mingli Deng* Dalton Transcations, 2023, 52, 9208-9214;>> Fulltext link
Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications , Mengmeng Zhang, Mingzhu Lu, Tianze Qiu, Qiao Wang, Zhenxia Chen, Mingli Deng, Yongtai Yang, Yannan Yang, Wei Li, Yun Ling,* and Yaming Zhou Small, 2023, 19(34), 2301894 >> Fulltext link
Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171 , Ruiqing Xiang, Mingzhu Lu, Tianze Wu, Chengbin Yang, Yu Jia, Xiaofeng Liu, Mingli Deng,**, Yu Ge, Jun Xu, Tong Cai, Yun Ling, Yaming Zhou,* European Journal of Medicinal Chemistry, 2023, 223, 257, 115514 >> Fulltext link
Design, synthesis and in vitro biological evaluation of 2-aminopyridine derivatives as novel PI3Kδ inhibitors for hematological cancer, Chengbin Yang, Yimin Gong, Yunjian Gao, Mingli Deng, Xiaofeng Liu, Yongtai Yang, Yun Ling, Yu Jia*, Yaming Zhou*; Bioorg. Med. Chem. Lett., 2023, 82, 129152>> Fulltext link
Gadolinium-based contrast agents built of DO3A-pyridine scaffold: Precisely tuning carboxylate group for enhanced magnetic resonance imaging, Yongyin Geng, TianzeWu, Qiuyue Han, Yongtai Yang, Zhenxia Chen, Xuanxuan Li, Bo Yin, Yaming Zhou, Yun Ling*; Chinese Chemical Letters, 2023, 34, 107685>> Fulltext link
A Pyridinesulfonamide Derivative FD268 Suppresses Cell Proliferation and Induces Apoptosis via Inhibiting PI3K Pathway in Acute Myeloid Leukemia, Yi Chen, Tianze Wu, Chengbin Yang, Mingzhu Lu, Zhenxia Chen, Mingli Deng, Yu Jia, Yongtai Yang, Xiaofeng Liu, Hongyan Wang, Yun Ling,, Lei Lu,* Yaming Zhou*; PLoS ONE, 2022, 17(11):e0277893>> Fulltext link
Hybrid Nanomaterials for Cancer Immunotherapy, Jianing Li, Wanyue Lu, Yannan Yang*, Ruiqing Xiang, Yun Ling, Chengzhong Yu*, Yaming Zhou*; Advanced Science, 2022, 2204932>> Fulltext link
Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation, Feng-Yuan Wang, Tianze Qiu, Yun Ling, Yannan Yang,* and Yaming Zhou*; Angew. Chem. Int. Ed. , 2022, 61, e202209499>> Fulltext link
Unprecedented Ferromagnetic Exchange Coupling of a Square-Planar Cu4O unit in a scu-Type Porous Metal–Organic Framework and Its Reticular Chemistry, Tianze Qiu, Yongchen Wang, Yihan Li, Lin Zhu*, Zhenxia Chen, Yu Jia, Pu Zhao, Wei Shi, Yaming Zhou, and Yun Ling*; Cryst. Growth Des., 2022, 22, 7, 4005–4011>> Fulltext link
Hollow carbon nanospheres embedded with stoichiometric γ-Fe2O3 and GdPO4: tuning the nanospheres for in vitro and in vivo size effect evaluation, Hui Zhang, Jianping Zhang, Yi Chen, Tianze Wu, Mingzhu Lu, Zhenxia Chen, Yu Jia, Yongtai Yang, Yun Ling* and Yaming Zhou*; Nanoscale Advances, 2022, 4, 1414 >> Fulltext link
Development of Anti-Breast Cancer PI3K Inhibitors Based on 7-Azaindole Derivatives through Scaffold Hopping: Design, Synthesis and in Vitro Biological Evaluation, Chengbin Yang, Mingzhu Lu, Yi Chen, Ruiqing Xiang, Tianze Qiu, Yu Jia, Yongtai Yang, Xiaofeng Liu, Mingli Deng, Yun Ling, Yaming Zhou*; Bioorganic Chemistry, 2021, 117, 105405 >> Fulltext link
Ultrafine Fe-modulated Ni nanoparticles embedded within nitrogen-doped carbon from Zr-MOFs-confined conversion for efficient oxygen evolution reaction, Lingtao Kong, Zhouxun Li, Hui Zhang, Mengmeng Zhang, Jiaxing Zhu, Mingli Deng*, Zhenxia Chen, Yun Ling & Yaming Zhou, Frontiers of Chemical Science and Engineering, 2022, 16, 1114–1124 >> Fulltext link
Effect of Fluorination on the Crystal Structure， Stability and Gas Adsorption Property in Zinc（II） Metal-organic Frameworks, Xin Zhang, Zhenxia Chen, Yongtai Yang, Mingli Deng*, Linhong Weng; Chinese Journal of Structrual Chemistry, 2022, 41(2), 49-56 >> Fulltext link
Post-synthetic anchoring Fe(III) into a fcu-type Zr-MOF for the catalyzed hydrolysis of 5-hydroxylmethoxyfurfural, Mengmeng Zhang, Jiaying Lou, Rui Xu, Peng Li, Yunfei Sha, Hui Zhang, Yu Jia, Zhenxia Chen, Da Wu*, Yun Ling*, YamingZhou; Microporous Mesoporous Materials, 2021, 328, 111449 >> Fulltext link
Reticular Chemistry Approach to Explore the Catalytic CO2-epoxide Cycloaddition Reaction over Tetrahedral Coordination Lewis Acidic Sites in a Rutile-type Zinc-phosphonocarboxylate Framework, Lingtao Kong, Zhouxun Li, Han Hu, Jiaxing Zhu, Zhenxia Chen*, Mingli Deng*, Yun Ling, Peng Li, Yu Jia, Yaming Zhou; Chemical Engineering Journal, 2022, 427,131759 >> Fulltext link
Discovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity, Chengze Tian, Chengbin Yang, Tianze Wu, Mingzhu Lu, Yi Chen, Yongtai Yang, Xiaofeng Liu, Yun Ling, Mingli Deng, Yu Jia*, Yaming Zhou* Bioorganic & Medicinal Chemistry Letters, 2021, 48, 128271 >> Fulltext link
Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation, Chengbin Yang， Chenyue Xu， Zhipeng Li， Yi Chen， Tianze Wu， Hui Hong， Mingzhu Lu， Yu Jia, Yongtai Yang, Xiaofeng Liu, Mingli Deng, Zhenxia Chen, Qingquan Li*, Yun Ling*, Yaming Zhou* European Journal of Medicinal Chemistry, 2021, 223, 1136613 >> Fulltext link
Hollow carbon nanospheres dotted with Gd–Fe nanoparticles for magnetic resonance and photoacoustic imaging, Hui Zhang, Tianze Wu, Yi Chen, Qianqian Zhang, Zhenxia Chen, Yun Ling,* Yu Jia, Yongtai Yang, Xiaofeng Liu and Yaming Zhou* Nanaoscale, 2021, 13, 10943-10952 >> Fulltext link
Multimetal lanthanide phosphonocarboxylate frameworks: structure, colour tuning and near-infrared emission, Huiru Jing, Wenyan Dan, Jiaxing Zhu, Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu, Zhenxia Chen* and Yaming Zhou* Dalton Transcations, 2021, 50, 7380 - 7387 >> Fulltext link
TEA-assistant synthesis of MOF-74 nanorods for drug delivery and in-vitro magnetic resonance imaging, Jiaqi Hu, Yi Chen, Hui Zhang, Zhenxia Chen*, Yun Ling, Yongtai Yang, Xiaofeng Liu, Yu Jia, Yaming ZhouMicroporous Mesoporous Materials, 2021, 315, 110900 >> Fulltext link
Controlled syntheses of Mg-MOF-74 nanorods for Drug Delivery, Jiaqi Hu; Yi Chen; Hui Zhang; Zhenxia Chen*, Journal of Solid State Chemistry, 2021, 294, 121853 >> Fulltext link
Precise regulating synergistic effect in metal–organic framework for stepwise-controlled adsorption, Jiaxing Zhu, Yi Yu, Hongchuan Fan, Huaqiang Cai,* Zhenxia Chen, Linhong Weng, Yun Ling* and Yaming Zhou, Inorganic Chemistry Frontier, 2021, 8, 1666-1674 >> Fulltext link
In situ embedding dual-Fe nanoparticles in synchronously generated carbon for the synergistic integration of magnetic resonance imaging and drug delivery, Hui Zhang; Jianping Zhang; Qianqian Zhang; Xiaofeng Liu; Yongtai Yang; Yun Ling; Yaming Zhou*, Nanoscale Advances, 2020,2, 5296-5304 >> Fulltext link
Coordination and space confined preparation of nickel sub-nanoparticles within a metal-organic framework for catalytic degradation of methyl orange, Zhouxun Li, Hui Zhang, Lingtao Kong, Zhenxia Chen*, Yongtai Yang, Xiaofeng Liu, Mingli Deng*, Yaming Zhou, Journal of Environmental Chemical Engineering, 2020,8(5),104363 >> Fulltext link
Cobalt substitution in a flexible metal-organic framework: modulating a soft paddle-wheel unit for tunable gate-opening adsorption, Jiaxing Zhu; Junye Chen; Tianze Qiu; Mingli Deng*; Qingshu Zheng; Zhenxia Chen; Yun Ling*; Yaming Zhou, Dalton Transactions, 2019,48(21), 7100-7104 >> Fulltext link
A robust etb-type metal-organic framework showing polarity-exclusive adsorption of acetone over methanol for their azeotropic mixture, Han Hu; Jiaxing Zhu; Feilong Yang; Zhenxia Chen; Mingli Deng; Linhong Weng; Yun Ling*; Yaming Zhou, Chemical Communications, 2019,55(46), 6495-6498 >> Fulltext link
