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Inhibition of the cancer stem cell immune checkpoint SOAT1 suppresses regulatory T cell functions through a trans-cellular 20(S)-Hydroxycholesterol-GPR132 pathway in mice Yahui Ding, Wanqi Fang, Ruiqing Xiang, Haitao Liu, Menglin Huang, Yingran Shen, Ying Chen, Guohao Wang, Zhaocai Zhou, Yun Ling*, Ling V. Sun*, Yuetong Wang* & Steven X. Hou* Optimization of the fragment binding to hinge region for a potent PIM kinase inhibitor based on N-pyridinyl amide scaffold Mingzhu Lu, Haifeng Liu, Weidong Wang, Jianing Li, Tianze Wu, Mingli Deng, Yu Jia, Xiaofeng Liu, Yongtai Yang, Yun Ling*, Yaming Zhou* A macrocyclic gadolinium contrast agent bearing an assembly-dissociable feature with albumin for enhanced magnetic resonance imaging and in vivo profiles Yimin Gong, Yichen Yao, Zhuoying Ruan, Nan Mei, Dan Luo, Xiaofeng Liu, Yongtai Yang, Yu Jia, Yannan Yang, Bo Yin,* Yaming Zhou and Yun Ling* Preparation of nano-ferrite embedded porous carbon by gelothermal-pyrolysis strategy for advanced magnetic resonance imaging and photothermal performances Mengmeng Zhang*, Xin Zeng, Yimin Gong, WeiDong Wang, Jianing Li, Mingzhu Lu, Yun Ling, Yaming Zhou* Dual-Powered Nanomotor In Situ Vaccine with Tumor-Confined Penetration and Acidity Neutralization Boosts Stimulator of Interferon Genes-Mediated Immunotherapy Jianing Li, Yuanting Zhang, Weidong Wang, Yimin Gong, Yaming Zhou*, Yannan Yang* Geometry-Adaptive Coassembly of Binary Nanocrystal Superlattices with Tunable Translational and Orientational Order Ziyue Zheng, Hao Wang, Yutong Gao, Siyu Wan, Longfei Lv, Jing Yang, Dong Yang, Yun Ling*, Tongtao Li*, Angang Dong* Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy Xiang Liu, Weidong Wang, Tianze Wu, Jianing Li, Yimin Gong, Dan Luo, Xianling Guo*, Mingli Deng*, Yannan Yang* Reticular synthesis of a pcu-b framework: digital reticular chemistry for anisotropic modulation and multicomponent integration Xiaoming Lv, Yichen Yao, Jiaxing Zhu, Yun Ling,* Yaming Zhou and Zhenxia Chen* A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells Tianze Wu, Yi Chen, Yimin Gong, Mingzhu Lu, Chengbin Yang, Yannan Yang, Yun Ling* and Yaming Zhou* Topology-Dependent T2 Relaxivity in Fe₃O Cluster-Based MOFs for Enhanced Tumor Monitoring via MRI Qiao Wang, Yimin Gong, Jianing Li, Xin Zeng, Dan Luo, Yun Ling*, Yaming Zhou and Zhenxia Chen* Coordination-Dissociation Induced T1-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring Dan Luo, Tianze Wu, Tianze Qiu, Jianing Li, Yimin Gong, Jingting Weng, Zhenxia Chen, Yannan Yang, Bo Yin, Yun Ling*, Yaming Zhou Photocaging of N-pyridinyl amide scaffold-based PIM inhibitors for spatiotemporal controlled anticancer bioactivity Mingzhu Lu, Haifeng Liu, Ruiqing Xiang, Jianing Li, Tianze Wu, Mingli Deng, Yu Jia, Xiaofeng Liu, Yongtai Yang, Yu Ge, Tong Cai, Jianming Wu*, Yun Ling, Yaming Zhou* Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications Yimin Gong, Hui Zhang, Mingzhu Lu, Jiayu Sun, Yu Jia, Yannan Yang, Xiaofeng Liu, Bo Yin, Yaming Zhou, Yun Ling Journal of Colloid and Interface Science, 2025, 479, 412-421🔗 Fulltext link Hybrid nanoparticle–mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines Jianing Li, Tianze Wu, Weidong Wang, Yimin Gong, Mingzhu Lu, Mengmeng Zhang, Wanyue Lu, Yaming Zhou*, Yannan Yang* A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis Wanyue Lu, Weidong Wang, Yimin Gong, Jianing Li, Yaming Zhou*, Yannan Yang* Tadpole-like carbon nanotube with Fe nanoparticle encapsulated at the head and Zn single-atom anchored on the body: one-pot carbonization for tetramodal synergistic cancer therapy Mengmeng Zhang, Mingzhu Lu, Yimin Gong, Yannan Yang*, Junfei Song, Jianing Li, Zhenxia Chen, Yun Ling*, Yaming Zhou Reticular chemistry of the fcu-type Gd(III)-doped metal-organic framework for T1-weighted magnetic resonance imaging Tianze Qiu; Tianze Wu; Mingzhu Lu; Yuxi Xie; Mengmeng Zhang; Dan Luo; Zhenxia Chen; Bo Yin; Yaming Zhou; Yun Ling,* Discovery of N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide (FD274) as a highly potent PI3K/mTOR dual inhibitor for the treatment of acute myeloid leukemia Chengbin Yang, Yi Chen, Tianze Wu, Yunjian Gao, Xiaofeng Liu, Yongtai Yang, Yun Ling, Yu Jia, Mingli Deng*, Jianxin Wang, Yaming Zhou,* Nanosheets of two-dimensional photoluminescent Lanthanide phosphonocarboxylate frameworks decorated with free carboxylic groups for latent fingerprint imaging Dan Luo, Hongjie He, Huiru Jing, Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu, Zhenxia Chen* and Mingli Deng* Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications Mengmeng Zhang, Mingzhu Lu, Tianze Qiu, Qiao Wang, Zhenxia Chen, Mingli Deng, Yongtai Yang, Yannan Yang, Wei Li, Yun Ling,* and Yaming Zhou Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171 Ruiqing Xiang, Mingzhu Lu, Tianze Wu, Chengbin Yang, Yu Jia, Xiaofeng Liu, Mingli Deng,**, Yu Ge, Jun Xu, Tong Cai, Yun Ling, Yaming Zhou,* European Journal of Medicinal Chemistry, 2023, 223, 257, 115514🔗 Fulltext link Hybrid Nanomaterials for Cancer Immunotherapy Jianing Li, Wanyue Lu, Yannan Yang*, Ruiqing Xiang, Yun Ling, Chengzhong Yu*, Yaming Zhou*
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